More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
NATURE STRUCTURAL & MOLECULAR BIOLOGY(2014)
摘要
Enterovirus HEV71 is responsible for recurring epidemics in developing countries. New structural analyses coupled with in silico docking methods have allowed for the generation of potent inhibitors of viral-envelope uncoating that block subsequent insertion of viral RNA into the host cell.
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关键词
nature structural and molecular biology, science
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