Biosynthesis with fluorine.

Stephan Klopries,Kyra R M Koopmans,Elsa Sanchez-Garcia,Frank Schulz

CHEMBIOCHEM（2014）

引用 3|浏览11

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摘要

No longer in-F-able: fluorine building blocks can be used in polyketide biosynthesis. This represents a more flexible approach to organofluorines than the traditional use of fluorinated starter units in multistep organic syntheses, and will hopefully increase the number of compounds available for drug development.

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关键词

biocatalysis,biosynthesis,enzymes,fluorine,polyketides

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