Bradbury-Eggleston syndrome - an unusual cause of gastroesophageal reflux disease (GERD).

Igor D Jovanović, Dragana R Jovanović,Sanja Pavlović,Branislav Milovanović,Milenko Uglješić,Nikola Milinić,Mirjana Cvetković,Marija Branković,Goran Nikolić

Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina（2014）

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Abstract

The report presents a case of a 46-year-old male patient, previously treated because of dysphagia, pyrosis, vertigo while standing up and impotency. Manometric and pH-metric analysis showed presence of gastroesophageal reflux disease (GERD) caused by transient relaxation of lower esophageal sphincter (TRLES). Heart-rate variability showed decreased sympathetic function. Electromyoneurography showed a neurological lesion in muscles of upper extremities. The patient received midodrine and clonazepam which resolved this condition. These findings suggest that a neurological disorder can be a cause of GERD.

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