A new class of synthetic anti-lipopolysaccharide peptides inhibits influenza A virus replication by blocking cellular attachment.

Julia Hoffmann,Carola Schneider,Lena Heinbockel,Klaus Brandenburg,Rudolph Reimer,Gülsah Gabriel

Antiviral Research（2014）

引用 26|浏览7

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摘要

•Here, we show that SALPs inhibit influenza virus replication in vitro and in vivo.•SALPs specifically interact with N-Acetylneuraminic acids.•SALPs block influenza virus cellular attachment.

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关键词

Influenza virus,Synthetic anti-lipopolysaccharide peptides (SALPs),Cellular attachment inhibitor,Mouse model

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