Encoded Library Technology As a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium Tuberculosis InhA Lourdes Encinas , Heather O'Keefe , Margarete Neu , Modesto J. Remuinan , Amish M. Patel , Ana Guardia , Christopher P. Davie , Natalia Perez-Macias , Hongfang Yang , Maire A. Convery , Jeff A. Messer , Esther Perez-Herran , Paolo A. Centrella , Daniel Alvarez-Gomez , Matthew A. Clark , Sophie Huss , Gary K. O'Donovan , Fatima Ortega-Muro , William McDowell , Pablo Castaneda , Christopher C. Arico-Muendel , Stane Pajk , Joaquin Rullas , Inigo Angulo-Barturen , Emilio Alvarez-Ruiz , Alfonso Mendoza-Losana , Lluis Ballell Pages , Julia Castro-Pichel , Ghotas Evindar Journal of Medicinal Chemistry(2014)
Key words
Drug Target Identification
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