噬菌体治疗细菌感染的研究进展

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences(2013)

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Abstract
噬菌体是一种细菌依赖性病毒,在治疗细菌特别是耐药性细菌感染方面,与传统的抗生素比较具有独特的优势,其代谢动力学及给药途径是目前的研究热点.噬菌体裂解酶作为一种新的治疗手段,具有比活性噬菌体制剂更多的优点.文中就噬菌体在细菌感染治疗方面的作用机理、给药途径和基因工程的应用,及噬菌体裂解素的研究进展进行综述,对噬菌体治疗细菌感染提出展望.
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Key words
bacteriophage therapy,bacterial infection
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