Regulation of the yeast trehalose-synthase complex by cyclic AMP-dependent phosphorylation.

Biochimica et Biophysica Acta (BBA) - General Subjects(2014)

Cited 35|Views5
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Abstract
•Tsl1 is necessary to activate the trehalose synthase complex (TPS) in response to heat shock.•Trehalose-6-phosphate inhibits Tps1 activity.•TPS undergoes inhibition by cAMP-dependent phosphorylation, stopping trehalose synthesis during stress recovery.
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Key words
Trehalose,Saccharomyces cerevisiae,Stress response,Phosphorylation,Ras/cAPK pathway
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