Rapid induction of REDD1 gene expression in macrophages in response to stress-related catecholamines
Immunology Letters(2014)
Abstract
•REDD1 is characterized as a new host defense factor.•We examined effect of adrenaline and noradrenaline on macrophage expression of REDD1.•Adrenaline and noradrenaline upregulated REDD1 expression in macrophages.•β2-Adrenoceptor and cAMP appeared to be responsible for the REDD1 upregulation.
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Key words
Ab,Ad,AR,cAMP,Epac,GAPDH,IL,LPS,mTOR,mTORC1,NA,PCR,PKA,REDD1,RT,TNF
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