Solution structure of CEH-37 homeodomain of the nematode Caenorhabditis elegans.
Biochemical and Biophysical Research Communications(2014)
Abstract
•We have determined solution structures of CEH-37 homedomain.•CEH-37 HD has a compact α-helical structure with HTH DNA binding motif.•Solution structure of CEH-37 HD shares its molecular topology with that of the homeodomain proteins.•Residues in the N-terminal region and HTH motif are important in binding to Caenorhabditis elegans telomeric DNA.•CEH-37 could play an important role in telomere function via DNA binding.
MoreTranslated text
Key words
NMR,TBP,HD,C. elegans,NOE,HSQC
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined