Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo
NATURE(2013)
摘要
Understanding how RNA structure influences its function has been hampered by a lack of approaches that can accurately quantify RNA structure in vivo ; here, RNA structure is revealed on a global scale and with nucleotide-level resolution, showing that there is less structure within cells than expected from in vitro and in silico analyses.
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关键词
RNA, Sequencing
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