Bixin protects hepatocytes against 1,2-dimethylhydrazine-induced genotoxicity but does not suppress DNA damage and pre-neoplastic lesions in the colon of Wistar rats.
Mutation Research/Genetic Toxicology and Environmental Mutagenesis(2014)
Abstract
•Bixin has no genotoxic effect in liver and colon cells by comet assay.•Bixin significantly reduced the DNA damage in hepatocytes.•Bixin not reduce the frequency of DNA damage in colon cells.•Bixin not suppress the formation of pre-neoplastic lesions in colon.
MoreTranslated text
Key words
Bixin,Bixa orellana,Aberrant crypt foci,Comet assay
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined