Effect of vagus nerve stimulation on electrical kindling in different stages of seizure severity in freely moving cats.

Epilepsy Research(2014)

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摘要
•We analyzed the effects of vagus nerve stimulation (VNS) on amygdaloid kindling (AK).•VNS applied in stage I induces a delay to reach stage VI of AK.•VNS applied in stage II, III, and IV is non-protective against AK development.•VNS may modulate thalamo-cortical and cortico-thalamic excitability.
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关键词
Vagus nerve stimulation,Spike-wave discharge,Polyspike,Amygdala kindling,Anti-epilpetogenic
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