Optimized selection of anti-tumor recombinant antibodies from phage libraries on intact cells.
Molecular Immunology(2014)
摘要
•Phage antibody libraries derived from tumor-infiltrating lymphocytes were prepared.•For cell-based selection substrate was deprived of dead cells.•Selected anti-tumor antibodies recognized surface antigens of tumor cells.
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关键词
Phage antibody library,Cell-based selection
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