Suppression of Fas-mediated apoptosis via steric shielding by filovirus glycoproteins.

Osamu Noyori,Eri Nakayama,Junki Maruyama,Reiko Yoshida,Ayato Takada

Biochemical and Biophysical Research Communications（2013）

引用 10|浏览3

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摘要

•Filovirus GPs form a steric shield over the Fas molecule on the cell surface.•The steric shielding by filovirus GPs suppresses Fas-mediated apoptosis.•The steric shielding may be a common ability of all filoviruses thus far known.

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关键词

Filovirus,Glycoprotein,Steric shielding,Apoptosis,Fas

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