Reductions in Log P Improved Protein Binding and Clearance Predictions Enabling the Prospective Design of Cannabinoid Receptor (CB1) Antagonists with Desired Pharmacokinetic Properties.Bruce A. Ellsworth,Philip M. Sher,Ximao Wu,Gang Wu,Richard B. Sulsky,Zhengxiang Gu,Natesan Murugesan,Yeheng Zhu,Guixue Yu,Doree F. Sitkoff,Kenneth E. Carlson,Liya Kang,Yifan Yang,Ning Lee,Rose A. Baska,William J. Keim,Mary Jane Cullen,Anthony V. Azzara,Eva Zuvich,Michael A. Thomas,Kenneth W. Rohrbach,James J. Devenny,Helen E. Godonis,Susan J. Harvey,Brian J. Murphy,Gerry G. Everlof,Paul I. Stetsko,Olafur Gudmundsson,Susan Johnghar,Asoka Ranasinghe,Kamelia Behnia,Mary Ann Pelleymounter,William R. EwingJournal of Medicinal Chemistry(2013)引用 10|浏览55AI 理解论文溯源树样例生成溯源树,研究论文发展脉络Chat Paper正在生成论文摘要