Circulating CD56dim NK cells expressing perforin are increased in progressive multiple sclerosis.

Domenico Plantone,Alessandro Marti,Giovanni Frisullo,Raffaele Iorio,Valentina Damato,Viviana Nociti,Agata Katia Patanella,Assunta Bianco,Massimiliano Mirabella,Anna Paola Batocchi

Journal of Neuroimmunology（2013）

引用 24|浏览3

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摘要

In this study we evaluated the percentages of CD3−CD56bright, CD3−CD56dim, CD3−CD56brightperforin+ and CD3−CD56dimperforin+ Natural Killer (NK) cells in peripheral blood from untreated secondary progressive (SP) and primary progressive (PP) multiple sclerosis (MS) patients and age and sex matched healthy subjects.

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关键词

Progressive multiple sclerosis,Cytotoxicity,Natural Killer cells

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