Neutrophil chemotactic activity and histamine in atopic and nonatopic subjects after exercise-induced asthma.
AMERICAN REVIEW OF RESPIRATORY DISEASE(2015)
Abstract
Seven atopic and 6 nonatopic asthmatics with exercise-induced asthma were subjected to a treadmill exercise task. After this procedure, both groups had elevations in the concentrations of plasma histamine and serum high molecular weight neutrophil chemotactic activity (as assessed by Sephadex G-200 chromatography). These findings support the view that the release of mast-cell-associated mediators can be independent of the atopic state.
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Key words
neutrophil chemotactic activity,asthma,histamine,exercise-induced
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