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Identification of three novel Toxoplasma gondii rhoptry proteins

Ana Camejo,Daniel A. Gold,Diana Lu, Kiva McFetridge,Lindsay Julien,Ninghan Yang,Kirk D.C. Jensen,Jeroen P.J. Saeij

International Journal for Parasitology（2014）

Cited 27|Views14
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Abstract
•Three novel Toxoplasma gondii rhoptry proteins, ROP47, ROP48 and RON12, were identified.•ROP47 is secreted into the host cell and traffics to the host nucleus.•Deletion of ROP47 or ROP48 did not influence in vitro growth or virulence in mice.
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Key words
Toxoplasma gondii,Rhoptry,Rhoptry neck,Host–pathogen interaction
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