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DNA analysis based on toehold-mediated strand displacement on graphene oxide.

Takaaki Miyahata,Yusuke Kitamura,Akika Futamura,Hirotaka Matsuura,Kazuto Hatakeyama,Michio Koinuma,Yasumichi Matsumoto,Toshihiro Ihara

CHEMICAL COMMUNICATIONS（2013）

Cited 25|Views3
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Abstract
Fluorescent dye-labeled probe DNA was immobilized on fluorescence-quenching graphene oxide (GO) through a capture DNA. When targets were added, the probes were released from the GO through toehold-mediated strand exchange. Higher emission recovery and more signal contrast were achieved relative to conventional methods that are based on direct adsorption of probes.
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graphene oxide,dna analysis,toehold-mediated
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