New attenuated vaccine against columnaris disease in fish: choosing the right parental strain is critical for vaccine efficacy.

Haitham Mohammed,Oscar Olivares-Fuster,Stacey LaFrentz,Covadonga R Arias

Vaccine（2013）

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摘要

•Columnaris vaccine efficacy is related to the genetics of the avirulent mutants.•Genomovar II vaccines better prevent columnaris disease.•Avirulent mutant, 17-23, was identified as the best vaccine candidate.

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关键词

Catfish,Zebrafish,Tilapia,Columnaris disease,Flavobacterium columnare,Vaccine

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