Three-dimensional dynamic MR imaging with a volumetric interpolated breath-hold examination for solitary pulmonary lesions: correlation of contrast enhancement pattern with pathological features]
Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica(2004)
摘要
To evaluate the clinical feasibility of dynamic MR imaging of solitary pulmonary lesions (SPLs) using a fat-suppressed three-dimensional gradient-echo technique with a volumetric interpolated breath-hold examination (VIBE). Correlation between the enhancement pattern and the histological characteristics of the nodules was also assessed.Dynamic 3D-VIBE was performed in 16 patients with pathologically proven SPLs. Each lesion was analyzed for its internal enhancement pattern, dynamic enhancement pattern, and peripheral enhancement (PE).A heterogeneous pattern of internal enhancement was well correlated with histological observation of necrosis, cystic changes, and variously sized air spaces. The washout pattern was seen in the medullary parts of the nodules with little fibrous stroma. The progressive pattern was seen at foci of collapse in the alveolar structure, central scars, and prominent fibrosis. PE was also seen in 6 malignant lesions (43%), and was well correlated with the medullary growth of adenocarcinoma and marginal fibrosis with lymphocytic infiltration of squamous cell carcinoma. The presence of PE was statistically significantly related with tumor size (p < 0.05).Dynamic 3D-VIBE allows assessment of the histological characteristics of SPLs. It is also thought that this technique may be a promising method for differentiation between benign and malignant lesions.
更多查看译文
关键词
solitary pulmonary lesions,contrast enhancement pattern,volumetric,imaging,[three-dimensional,breath-hold
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要