Knockout mice in xenobiotic metabolism.

Colin J Henderson,Diana M E Otto,Aileen W McLaren,Dianne Carrie,C Roland Wolf

DRUG METABOLISM REVIEWS（2003）

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摘要

Mice in which genes for drug metabolizing enzymes have been deleted or inactivated have great potential to further our understanding of the functions of these enzymes and their role in toxicology a...

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关键词

cytochrome P450 reductase, conditional deletion, liver, mouse

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