FLOW CYTOMETRIC CROSS-MATCHING AND OUTCOME ONE YEAR AFTER RENAL-TRANSPLANTATION

Previous studies have shown that flow cytometric crossmatch assays can identify an at risk population in renal transplantation [1-5]. We used the assay for recipient selection for 1 year. Recipients with donor T cell directed IgG were excluded from transplantation and those with B cell directed IgG were treated with increased immunosuppression. The transplants performed over this period (n = 126) were compared with an earlier series (n = 118) in which flow cytometric crossmatch results did not influence patient management. The results were evaluated for mortality and graft outcome at 3 months and 1 year. In addition, postoperative complications and duration of hospital stay were also assessed.