A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo.

Vijayan Gangadharan,Deepitha Selvaraj,Martina Kurejova,Christian Njoo,Simon Gritsch,Dagmar Škoricová,Heinz Horstmann,Stefan Offermanns,Andrew J Brown,Thomas Kuner,Anke Tappe-Theodor,Rohini Kuner

PAIN®（2013）

引用 29|浏览9

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摘要

Lysophosphatidylinositol (LPI) is a novel regulator of peripheral sensory neuron function and pathological pain. The roles of GPCR and non-GPCR components to the biological function of LPI are delineated.

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关键词

LPI,GPR55,G-proteins,Peripheral sensitization,Cancer pain

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