Immunomodulatory effects of the aromatic geranyl derivative filifolinone tested by the induction of cytokine expression.
Developmental & Comparative Immunology(2013)
Abstract
•Filifoline is an aromatic geranyl derivative obtained by semi-synthesis.•Filifolinone is a potential alternative immunomodulator for veterinary use.•Filifolinone increases pro-imflammatory and anti- imflammatory cytokynes in SHK-1 cells.•In Atlantic salmon, filifolinone upregulates cytokines involved in Th1-type responses.
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Key words
Immunostimulant activity,Filifolinone,Cytokines,Ribomunyl
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