Arecoline inhibits and destabilizes agrin-induced acetylcholine receptor cluster formation in C2C12 myotubes.
Food and Chemical Toxicology（2013）
摘要
•Arecoline inhibits the formation of agrin-induced AChR clusters in C2C12 myotubes.•Arecoline destabilizes agrin-induced and spontaneous AChR clusters in C2C12 myotubes.•Arecoline inhibits the expression of myogenin in C2C12 myotubes.
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关键词
ACh,AChR,FAS,FASD,LRP4,MG,MuSK,NMJ,PBS,SMA,STAT3
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