DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels.
Molecular Genetics and Metabolism(2013)
Abstract
•Plasma LCAT activity and ApoA-I level are decreased in mice overexpressing Dyrk1a.•Hepatic STAT3 activation is decreased in Dyrk1a transgenic mice.•SHP2 activation is increased in Dyrk1a transgenic mice.
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Key words
Apo,BAC,BSA,DS,DYRKs,ES,HDL,HRP,HSA21,LCAT,Q-PCR
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