In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos
Chemosphere(2013)
摘要
•PFCs are proved to be developmental toxicants.•Embryos exposed to PFCs develop various abnormalities.•Heart- and liver-specific RNAs are significantly down-regulated by exposure to PFCs.•Heart defects and hepatomegaly are induced by PFCs.
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关键词
Perfluoroalkyl compounds,Comparative toxicology,Developmental toxicity,Teratogenecity,Xenopus
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