Completion of the entire hepatitis C virus life cycle in genetically humanized mice

Marcus Dorner,Joshua A. Horwitz,Bridget M. Donovan,Rachael N. Labitt,William C. Budell,Tamar Friling,Alexander Vogt,Maria Teresa Catanese,Takashi Satoh,Taro Kawai,Shizuo Akira,Mansun Law,Charles M. Rice,Alexander Ploss

NATURE（2013）

引用 260|浏览27

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摘要

The entire hepatitis C virus life cycle can be recapitulated in an inbred mouse model, allowing preclinical assessment of antiviral therapeutics and vaccines.

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关键词

nature,virus replication,genetic engineering,cell line

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