Overlap of epitopes recognized by anti-carbonic anhydrase I IgG in patients with malignancy-related aplastic anemia-like syndrome and in patients with aplastic anemia
Immunology Letters(2013)
摘要
•We identify immunodominant epitopes of CA I recognized by specific autoantibodies.•We compare antibodies isolated from sera of patients with AA and AA-like syndrome.•Antibodies from both groups of patients recognize the same CA I epitopes.•Overlap of epitopes may indicate common pathophysiological mechanisms.
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关键词
Carbonic anhydrase I,Epitope extraction,Anti-CA I autoantibodies,Aplastic anemia,LC–MS/MS
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