MammaPrint Pre-screen Algorithm (MPA) reduces chemotherapy in patients with early-stage breast cancer.

Kathleen A Grant,Justus P Apffelstaedt,Colleen A Wright,Ettienne Myburgh, Rika Pienaar,Manie De Klerk,Maritha J Kotze

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde（2013）

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Abstract

The 70-gene profile classifies approximately 40% of early-stage breast cancer patients as low-risk compared with 15% using conventional criteria. In comparison, more than 60% were shown to be low risk with use of the MPA validated in this study as an appropriate strategy to prevent chemotherapy overtreatment in patients with early-stage breast cancer.

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