Carotenoids as possible interphotoreceptor retinoid-binding protein (IRBP) ligands: a surface plasmon resonance (SPR) based study.

Preejith P Vachali,Brian M Besch,Federico Gonzalez-Fernandez,Paul S Bernstein

Archives of Biochemistry and Biophysics（2013）

引用 37|浏览3

暂无评分

摘要

•Interphotoreceptor retinoid-binding protein (IRBP) binds a variety of ligands.•A surface plasmon resonance biosensor was employed to study these interactions.•IRBP is able to bind carotenoids and retinoids with similar affinities.•IRBP has 10times less affinity for ocular fatty acids.•IRBP may function as a carrier of carotenoids across the interphotoreceptor matrix.

查看译文

关键词

Carotenoids,Interphotoreceptor matrix,Interphotoreceptor retinoid-binding protein,Macular pigments,Retinoids,Surface plasmon resonance

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要