Comet assay and air-liquid interface exposure system: a new combination to evaluate genotoxic effects of cigarette whole smoke in human lung cell lines.

Susanne Weber,Marco Hebestreit,Torsten Wilms,Lynda L Conroy,Gregory Rodrigo

Toxicology in Vitro（2013）

引用 37|浏览2

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摘要

•Repeatable dose–response relationship between DNA damage and whole smoke in cells.•In vitro setups accurately reflecting human cigarette smoke exposure.•Comet assay and VITROCELL® 24 a new in vitro test system to screen whole smoke.

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