Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies
NATURE BIOTECHNOLOGY(2013)
Abstract
In a bacterial expression system, two half antibodies, each having distinct light chains, spontaneously assemble into an intact bispecific molecule with natural antibody architecture
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Key words
Antibody generation,Antibody therapy,Targeted therapies,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics
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