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Biosynthesis of the natural fluorophore legioliulin from legionella.

Tilman Ahrendt,Melissa Miltenberger,Ina Haneburger,Ferdinand Kirchner,Max Kronenwerth,Alexander O Brachmann,Hubert Hilbi,Helge B Bode

CHEMBIOCHEM（2013）

Cited 12|Views34
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Abstract
Let it shine: The biosynthesis of the UV fluorophore legioliulin (1) from Legionella spp. was elucidated and the phenylalanine ammonium lyase LglD responsible for the formation of the starter unit cinnamic acid was biochemically characterized. Additionally, two novel derivatives differing in the starter unit have been identified by mutasynthesis experiments.
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Key words
biosynthesis,Legionella,mutagenesis
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