The Cosmetics Europe strategy for animal-free genotoxicity testing: project status up-date.

S Pfuhler,R Fautz,G Ouedraogo,A Latil,J Kenny,C Moore,W Diembeck,N J Hewitt,K Reisinger,J Barroso

Toxicology in Vitro（2014）

引用 51|浏览7

暂无评分

摘要

•Overview of the Cosmetics Europe Genotoxicity Task projects.•Improved specificity by selecting relevant cells and sensitive toxicity measures.•Develop and validate human 3D skin models for micronucleus and Comet assays.•Investigated enzyme capacities of human skin and RS models.•Initial assay predictivity improved and new models for genotoxic hazard assessment.

查看译文

关键词

Genotoxicity,Cosmetics,Alternatives to animal testing,3D,Skin,Metabolism

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要