SAP modulates B cell functions in a genetic background-dependent manner.

Cynthia Detre,Burcu Yigit,Marton Keszei,Wilson Castro,Erica M Magelky,Cox Terhorst

Immunology Letters（2013）

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摘要

•Anti-CD40 in part re-activates humoral responses that are impacted by SAP deficiency.•SAP deficiency affects B cell responsiveness in a genetic background-dependent manner.•Environmental factors affect the severity of humoral deficiencies of SAP−/− mice.

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关键词

SAP,XLP,SLAM-family receptors

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