Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments

Nature methods(2013)

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摘要
method to tightly attach cell-derived extracellular matrix (ECM) to the culture surface is described. It is applied to generate bone marrow mesenchymal stem cell–derived ECM, which supports culture of human hematopoietic stem and progenitor cells.
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关键词
Biomaterials, Mesenchymal stem cells, Haematopoietic stem cells, Stem-cell niche
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