Cloning and functional characterization of the Lymantria dispar initiator caspase dronc.

Koji Kitaguchi,Rina Hamajima,Hayato Yamada,Michihiro Kobayashi,Motoko Ikeda

Biochemical and Biophysical Research Communications（2013）

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摘要

•We cloned a Lymantria dispar initiator caspase dronc (ld-dronc) from Ld652Y cells.•Overexpression of Ld-Dronc triggered apoptosis in Ld652Y cells.•Ld-Dronc was involved in apoptosis triggered by NPV infection.•Processing of Ld-Dronc occurred more rapidly than that of Dronc from Bombyx mori.

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关键词

Dronc,Initiator caspase,Lymantria dispar,Bombyx mori,Baculovirus,NPV

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