Interaction characteristics of Plexin-B1 with Rho family proteins.

Eyad Kalawy Fansa,Radovan Dvorsky,Si-Cai Zhang,Dennis Fiegen,Mohammad Reza Ahmadian

Biochemical and Biophysical Research Communications（2013）

引用 17|浏览17

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摘要

•Plexin-B1 binds to Rac and Rnd isoforms and RhoD, but not to RhoA, Cdc42, RhoG, or Rif.•Rnd1 efficiently displaces Rac1 from its complex with Plexin-B1 but not vice versa.•A negatively charged loop may facilitate Plexin-B1 interactions with Rho proteins.

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关键词

Interaction selectivity,Plexin-B1,Rho GTPases,Competitive interaction

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