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Presynaptic kainate receptor-mediated bidirectional modulatory actions: mechanisms.

Talvinder S Sihra,Antonio Rodríguez-Moreno

Neurochemistry International（2013）

Cited 39|Views4
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Abstract
•KARs have an autoreceptor role in modulating glutamate release.•KAR-mediated depression of glutamate release involves iono- and metabotropic actions.•KAR-mediated facilitation of glutamate release is independent of G-proteins.•KAR-mediated facilitation of glutamate release involves calcium signaling.•KAR-mediated facilitation of glutamate release involves calcium–calmodulin.
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Key words
Kainate receptors,Modulation,Glutamate,GABA,Ionotropic,Metabotropic,Subunits
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