Evaluation of the role of MAPK1 and CREB1 polymorphisms on treatment resistance, response and remission in mood disorder patients.

Raffaella Calati,Concetta Crisafulli,Martina Balestri,Alessandro Serretti,Edoardo Spina,Marco Calabrò,Antonina Sidoti,Diego Albani,Isabelle Massat,Peter Höfer,Daniela Amital,Alzbeta Juven-Wetzler,Siegfried Kasper,Joseph Zohar,Daniel Souery,Stuart Montgomery,Julien Mendlewicz

Progress in Neuro-Psychopharmacology and Biological Psychiatry（2013）

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摘要

Treatment resistant depression (TRD) is a significant clinical and public health problem. Among others, neuroplasticity and inflammatory pathways seem to play a crucial role in the pathomechanisms of antidepressant efficacy.

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关键词

TRD,SNPs,MDD,BD,MAPK1,CREB1,TRD-W,TRD-DC,HWE,LD

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