Implications of Tumor Location on Subtypes of Medulloblastoma.

Wan-Yee Teo,Jianhe Shen,Jack Meng Fen Su,Alexander Yu,Jian Wang,Wing-Yuk Chow,Xiaonan Li,Jeremy Jones,Robert Dauser,William Whitehead,Adekunle M. Adesina,Murali Chintagumpala,Tsz-Kwong Man,Ching C. Lau

Pediatric Blood & Cancer（2013）

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摘要

Medulloblastoma (MB) comprises of four molecular subtypes, Sonic hedgehog (SHH), Wingless (WNT), Groups 3 and 4. WNT‐subtype MBs were found to arise from midline of the brainstem occupying the fourth ventricle while SHH‐subtype occupied the cerebellar hemisphere in a small subset of patients.

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关键词

medulloblastoma,molecular subtypes,pediatric,tumor location

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