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A cell-free nanofiber composite scaffold regenerated osteochondral defects in miniature pigs.

Eva Filová,Michala Rampichová,Andrej Litvinec,Milan Držík,Andrea Míčková,Matej Buzgo,Eva Košťáková,Lenka Martinová,Dušan Usvald,Eva Prosecká,Jiří Uhlík,Jan Motlík,Luděk Vajner,Evžen Amler

International Journal of Pharmaceutics（2013）

Cited 57|Views1
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Abstract
The aim of the study was to evaluate the effect of a cell-free hyaluronate/type I collagen/fibrin composite scaffold containing polyvinyl alcohol (PVA) nanofibers enriched with liposomes, basic fibroblast growth factor (bFGF) and insulin on the regeneration of osteochondral defects.
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Key words
Cartilage,Fibrin,Nanofibers,Growth factors,Polyvinyl alcohol,Hyaluronic acid
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