Cascade synthesis of (E)-2-alkylidenecyclobutanols.

J R Falck,Anish Bandyopadhyay,Narender Puli,Abhijit Kundu,L Manmohan Reddy,Deb K Barma,Anyu He,Hongming Zhang,Dhurke Kashinath,Rachid Baati

Organic letters（2009）

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摘要

A facile, one-pot reaction cascade condenses 1,1,1-trichloroalkanes with alpha,beta-unsaturated ketones to unexpectedly furnish moderate to good yields of (E)-2-alkylidenecyclobutanols.

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