Understanding of two-stage continuous microreaction technology for in-situ generation and consecutive conversion of diazomethane

Journal of the Taiwan Institute of Chemical Engineers(2019)

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摘要
•A two-stage MRT is developed for continuous CH2N2 generation and utilization.•The interlinked reaction chemistry and engineering issues are distinguished.•The heat management is not a dominant factor for the low product yield in microreactor.•The low product yield mainly arises from the detrimental effect of water solvent.
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关键词
Microreaction technology,Diazomethane,Methyl-esterification,Heat transfer,Solvent effects
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