Staphylococcal meningoencephalitis, nematodiasis, and typhlocolitis in a squirrel monkey (Saimiri sciureus).

Background Seizures were observed in a 16-year old male Guyanese squirrel monkey with a history of inappetence and weakness. Methods and results Complete blood count, biochemical profile, and urinalysis indicated systemic disease. Nematode larvae were detected in the feces. Cerebrospinal fluid (CSF) analysis revealed leukocytes and gram-positive cocci. Staphylococcus aureus was isolated from the CSF. Histopathological evaluation revealed systemic lesions with inflammation and nematodes in the small and large intestine. Conclusion This is the first report describing spontaneous staphylococcal CNS infection in a squirrel monkey.