Precursors and propeptides of neurotrophic factors as modulators of the biological activity of mature forms

L. M. Rafieva, A. V. Shubin,E. V. Gasanov

Bioorganicheskaia khimiia（2012）

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摘要

Problems of the maturation of neurotrophic factors, the role of their precursors (proneurotrophins), and the contribution of elements that are removed in the course of maturation (propeptides) to the biological functions of these growth factors, are reviewed.

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关键词

neurotrophins,proneurotrophins,neurotrophic factors,propeptide,folding

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