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Synthesis and anticancer activity of 5 '-phthaloyinucleosides

A Orzeszko,J Vilpo,L Vilpo,B Kaminska

Die Pharmazie（2003）

Cited 26|Views2
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Abstract
A series of novel 5'-phthaloylnucleosides were synthesized via Mitsunobu reaction starting from AZT or 2'-deoxyadenosine and numerous phthalimides and their sulphur analogues-thioimides. Some of them showed significant anticancer activity.
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Key words
anticancer activity
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