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Direct amide formation using radiofrequency heating.

Thomas K Houlding,Kirill Tchabanenko,Md Taifur Rahman,Evgeny V Rebrov

ORGANIC & BIOMOLECULAR CHEMISTRY（2013）

Cited 39|Views7
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Abstract
We present a simple method for direct and solvent-free formation of amides from carboxylic acids and amines using radiofrequency heating. The direct energy coupling of the AC magnetic field via nickel ferrite magnetic nanoparticles enables fast and controllable heating, as well as enabling facile work-up via magnetic separation.
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Key words
Amine Synthesis,Amide Bond Formation,Nanomaterials Synthesis
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